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This combination reflects the least biological background, reduced matrix effects by offline fractionation and more certain detection by following selective transitions at matching retention times of peptides modified by the isomeric labeling reagent
Seelig GF, Simondsen RP, Meister A
(1996) Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in seleniumocysteine metabolism
This dysregulation increases iron storage, promoting M1 polarization (89)
