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Hallmarks of aging: an expanding universe

Peripheral serotonin in hypothyroidism and CFS has previously received little attention, and S-5-HT measurements have been used mainly in the carcinoid tumors/syndrome

By contrast, this difference in nerve distribution could also be a reflection of the unique architecture and sinusoidal vasculature of the bone marrow, as both locally released and circulating neurotransmitters may be able to distribute throughout the bone marrow more easily than in the collagen-rich peripheral adipose tissues