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AR-negative cell lines, such as DU145 and PC3, have also increased levels of repressive H3K9me2 marks and a reduction of active marks (H3K4me3 and H3K9ac) at the AR gene promoter [73]
Primarily, the interactions among R groups creates the complex three-dimensional tertiary structure of a protein
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In contrast, cytoplasmic PI(4,5)P 2 puncta in QKO embryos were not associated with PPK-1, suggesting that aberrant accumulation of PI(4,5)P 2 in QKO embryos was not caused by ectopic recruitment of PPK-1 to endosomes (Supplementary Fig
