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Convergence has been reported at the levels of STAT5 and SOCS3 (61) as well as on the major insulin signaling pathway: insulin receptor substrates (IRS) 1 and 2, PI 3-kinase, Akt, and extracellular regulated kinases (ERK) 1 and 2 (62,63)
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This intricate complex is subsequently transported across the cell by transport proteins and released into the bloodstream for circulation
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