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As a consequence, both cycles sustain liver injury through continuous, irreversible chain reactions, with copper posing a greater risk due to its higher hepatic levels compared to iron [27]

Dutta, D., Pulsipher, A., Luo, W., Mak, H

Positive results from the Phase II WILLOW study and Phase III ASPEN study demonstrate that compared to placebo controls, DPP1 inhibition treatment can significantly extend time intervals to first acute exacerbations in bronchiectasis patients and effectively reduce overall acute exacerbation occurrence frequency (Zhong et al., 2025

[DOI] [PMC free article] [PubMed] [Google Scholar] 243.Kolstad E, Bjrk M, Gilhus NE, Alfstad K, Clench-Aas J, Lossius M