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The methodological quality of the included studies, as assessed through the Jadad and NewcastleOttawa scales, varied from moderate to high, while the GRADE assessment indicated moderate certainty of evidence for serum vitamin B12 increase and low certainty for homocysteine reduction
Lipolysis is associated with improved metabolic health
Their effect on body composition in research is driven substantially through reduced energy intake and improved insulin dynamics, not through direct action on fat cells
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