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Besides the aforementioned complex neuroendocrine interactions, a proper adrenal gland GC response during stress depends on the availability of cholesterol the major substrate for steroidogenesis [67], hereditary factors [68], and the crosstalk between multiple cell types coexisting in the adrenal microenvironment, such as adrenocortical, chromaffin, endothelial, neuronal, immune, and glial cells [69, 70]
Martinez De Toda I, Miguelez L, Vida C, Carro E, De La Fuente M
In addition, TIM3 inhibition may prime the recruitment of cytotoxic T cells or reinvigoration of exhausted T cells to the tumor site under the metastatic setting
The proximity of mast cells to peripheral nerve endings suggests that they can be activated by neurotransmitters released by nerves after tendon injury (104)
