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Differentiation of 3T3-L1 pre-adipocytes 3T3-L1 pre-adipocytes cells were cultured with standard culture media (DMEM, 4.5 g/L glucose, L-glutamine, sodium pyruvate, 10% FBS, 1% antibiotic-antimycotic solution) and grown for 48 h before initiating differentiation using the manufacturer's suggested protocol and modified from previous published work.[18] Briefly, standard culture media was supplemented with scheduled addition of adipogenic agents [3-isobutyl-1methyl xanthine (IBMX), Sigma Aldrich

This sulfur-containing nutrient is produced in the liver

Another study involving 51 women found that curcumin improved insulin sensitivity (QUICKI index) after six weeks of supplementation but did not significantly alter lipid or glycemic markers compared to placebo [203]

Mech Ageing Dev 2010