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Astaxanthin treatment ameliorates ER stress in polycystic ovary syndrome patients: A randomized clinical trial

Urban air pollutants, including particulate matter (PM), ozone (O), and nitrogen dioxide (NO), have been shown to penetrate the stratum corneum and directly induce OS by activating toll-like receptors (TLRs) and the aryl hydrocarbon receptor (AhR) pathway [22]

In addition, ferroptosis inducers such as erastin and Sorafenib significantly upregulated the protein expression level of S1R but not the mRNA level, suggesting a transcription-independent role of S1R in ferroptosis [152]

Cytochrome P450 4F2 (CYP4F2) initiates -oxidation of tocochromanols, a process that is followed by -oxidation to carboxyethyl hydroxychromanol (CEHC), which can be conjugated with glucuronide or sulfate and excreted in urine or bile