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When premature infants are born, their lungs are still in the growth stage, and hyperoxia causes poor lung development, increases death of alveolar epithelial cells, and triggers pulmonary vascular remodeling

FIGURE 8 FIGURE 9 In the case of MAO-B14 , the interaction profile closely corresponded to that of istradefylline

All subsequent sample preparation and mass spectrometry data acquisition was conducted exactly as previously described 17

Funding This research was funded by the National Council of Science and Technology (CONACYT Ciencia Bsica grant number A1-S-8774) and the Universidad de Guadalajara through Fortalecimiento de la Investigacin y el Posgrado 2020