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[78] demonstrated that as early as in the first trimester, women who will develop placental insufficiency showed increased arterial stiffness and higher central aortic systolic blood pressure (SBPAo) than women with normotensive pregnancies did

Funding This project was financed by the National Natural Science Foundation of China (grant number 31871169 to YT, 81600040 to A-PW), Innovation guidance project of Hu Nan (grant number 2018SK51606 to S-XG, 2018SK51703 to NL), the province Natural Science Foundation of Hu Nan (grant number 2020JJ8032 to YT, 2021JJ30601 to A-PW)

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Intracerebral hemorrhage (ICH) accounts for 1520% of all stroke incidents, with the highest mortality in all subtypes of stroke, leading to serious social burden ( Neuron apoptosis occurs in ICH is the major reason for the poor prognosis following ICH injury ( Glycyl-l-histidyl-l-lysine (GHK) is a kind of human tripeptide consist of GHK