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In this review, we summarize and discuss some recent exciting discoveries in EBV research area, which including DNA methylation alterations, metabolic reprogramming, the changes of mitochondria and ubiquitin-proteasome system (UPS), oxidative stress and EBV lytic reactivation, variations in non-coding RNA (ncRNA), radiochemotherapy and immunotherapy

ADH = Antidiuretic hormone (vasopressin) ARBs = Angiotensin receptor blockers BBB = Blood brain barrier BKN = Bradykinin CFS = Chronic Fatigue Syndrome COMT = Catechol-O-methyltransferase CRH = Corticotropin-releasing hormone CVOs = Circumventricular organs DAO = Diamine oxidase EDS = Ehlers Danlos syndrome FB = Fibromyalgia Glu = Glutamate GnRH = Gonadotropin releasing hormone Hcy = Homocysteine HNMT = Histamine N-methyltransferase HPA = Hypothalamus-pituitary-adrenal LC = Long COVID MCAS = Mast cell

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