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Anatomy and cellular functions of the liver

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RNA isolation was conducted using the RNAqueous-Micro Total RNA Isolation Kit (Thermo, AM1931) according to the manufacturers instructions

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Oxidative stress happens when your body is out of balance between free radicals and antioxidants

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[ 38 ] In contrast, antioxidants, such as vitamins C and E and Nacetylcysteine (NAC), prevent BACH1 degradation and inhibit the release of free heme by lowering ROS levels, [ 39 ] since ROS stimulates free heme release through the oxidization of hemecontaining proteins

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