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A small interstitial cystitis pilot study reported improvement in 12 women after BPC-157 injections around bladder inflammation, but that was also early, small, and not enough to settle efficacy (PubMed)

However, chemical degradation studies have indicated it is a polymer that is biosynthesized from 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid, which are derived from dopamine and DOPA, respectively [476,484]

It does this by activating endothelial nitric oxide synthase, which is responsible for the production of nitric oxide a potent vasodilator
