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This suggestion is based on findings that NAC administration has been shown to improve negative scale and total scores of the Positive and Negative Syndrome Scale (PANSS), although no significant changes were seen in the positive scale [62,63,64,65]
Among the population groups at risk are older people, vegetarians, pregnant women, and patients with renal or intestinal diseases

Int J Dev Neurosci (2018) 67:4650

The role of metformin on vitamin B12 deficiency: a meta-analysis review
