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Description
The pigment neuromelanin (NM) is found at high concentrations in the SN and locus coeruleus (LC), where it is synthesised through polymerisation of dopamine-protein adducts 40

Given their rapid growth and aberrant blood vessel development, these cells are typically hypoxic, which is made worse by photosensitizer-mediated O 2 depletion [239]

doi: 10.1074/jbc.M300755200 31 HillK

Age-related hearing impairment and the triad of acquired hearing loss
