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Description
It caused increased ROS production, subsequent inhibition of aldehyde dehydrogenase (ALDH) and NF-B signaling

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Trans-omics: how to reconstruct biochemical networks across multiple omic layers

In ovarian cancer, SIRT1 inhibits the transcriptional activity of HIF-1 through deacetylation, thereby preventing the mesenchymal transformation of ovarian cancer cells 42
