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In summary, this study demonstrated an improvement in pain with a vitamin supplementation regime inclusive of B12 but did not show improved efficacy with addition of folate [31]

Acknowledgements We thank Nicole Barucci, Lori Lopresti-Morrow, and George Mourgkos from ATP R&D for supporting the in vivo studies, Elizabeth Elliot for her operational support at Aethon Therapeutics and assistance with manuscript submission, and William Rice, Bing Wang, and Huihui Kuang from the NYU Langone Healths CryoElectron Microscopy Laboratory (RRID: SCR_019202)

5 The lens naturally contains high levels of antioxidants, including ascorbic acid (vitamin C) and glutathione, which work together to help keep the lens clear

This mechanism underpins its fibroblast migration-promoting effects and helps explain its capacity to accelerate tissue repair at a cellular motility level independent of proliferation