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The nuclear receptors mainly contain ESR1 (also called ER) and ESR2 (also named ER), while the membranous receptor is G protein-coupled estrogen receptor (GPER1)

Plants 23 , 249268 (2017)
Secondly, current culture media do not support correct maintenance of methylation, even in mouse embryos that have passed the standard Mouse Embryo Assay (MEA) for toxicity [24]
