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also talked about the relationship between IL-17 inhibition and exacerbation of colitis
Cojocaru et al., 2020)
MMP-9 and MMP-13 inhibition has been shown to abolish syndecan-1 shedding in rat-fad-pad endothelial cells, reinforcing the major role of these proteases in glycocalyx shedding (327)
Beyond small clinical cohorts, large-scale patient outcome data strongly supports the use of these compounds
