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A 2015 study published in the Annals of Clinical and Laboratory Science found that intra-articular (injected into the joint) AOD-9604 enhanced cartilage regeneration in a rabbit model of knee osteoarthritis

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However, its endocrine effects may influence the action or monitoring of certain medications

While it has not received FDA approval for therapeutic use, it is available for research purposes and is used in metabolic optimization protocols
