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Furthermore, with respect to dopaminergic signaling, a reduction in anxiety-like behaviors and an increase in locomotor activity in 3xTg mice are accompanied by an increase in postsynaptic D2 dopamine receptors in the striatum and in D2-autoreceptors in substantia nigra/VTA cell bodies (Gloria et al., 2021)

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Despite evidence of complex interactions between genetics and environment in mediating CAD risk [95, 96], existing linear risk prediction models including genetic risk often do not capture genegene or gene-environmental interactions in risk assessment [97,98,99,100]

Electroacupuncture exerts anti-inflammatory effects in cerebral ischemia-reperfusion injured rats via suppression of the TLR4/NF-B pathway