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For context, GHK-Cu has been formally reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel, the industry body that assesses cosmetic ingredient safety in the US, and found safe as used at typical cosmetic concentrations
According to the available scientific data, research experiments in rodents have lasted up to 45 days, with most studies ranging between 11-45 days or four weeks on average [3, 4, 7]

Ongoing inflammatory conditions can affect B12 status

These include people who: Have an autoimmune disorder such as vitiligo Have a gastrointestinal disorder such as coeliac disease or Crohns Have stomach ulcers, atrophic gastritis, or an abnormally thin stomach lining Follow a vegan diet Take certain medications Are entering their senior years BENEFITS OF B12 INJECTIONS FOR BACK PAIN Vitamin B12 has been shown to be beneficial in supporting our nervous system to function properly