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[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Pei Y, Du Q, Liao PY, Chen ZP, Wang D, Yang CR, et al

This improved ability to control intracellular mycobacteria could be through the improved redox homeostasis in the cell and possibly through modulation of cytokines that result in a more effective immune response against these infections

However, accumulating evidence suggests that all LDH isoforms retain the inherent capacity to mediate pyruvate-to-lactate conversion accompanied by NAD+ regeneration, and that LDHA and LDHB can functionally compensate for each other under metabolic stress (44,45)