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Methylene blue applied topically acts as an antioxidant in skin care, which is well accepted approach to delay the skin aging process The safe methylene blue dosage in humans ranges from .5 mg to 4 mg/kg (e.g

More recently, enhanced ROS levels have been observed in a wide variety of pathological states, such as neurodegenerative, autoimmune, cardiovascular, and metabolic diseases [21, 28, 164, 165], atherosclerosis [166, 167], cataracts [168], Fanconi anemia (FA), and hematological malignancies such as MDS, and AML

283 2252922540 10.1074/jbc.M801925200 [DOI] [PMC free article] [PubMed] [Google Scholar] Ozcan U., Yilmaz E., Ozcan L., Furuhashi M., Vaillancourt E., Smith R

Methods 25, 402408 (2001)