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Because the body is efficient at excreting excess B12 through urine, there is no established tolerable upper intake level (UL) for the vitamin
Patients with early hereditary optic nerve atrophy, cyanocobalmin hypersensitivity, and those who are pregnant
The addition of the N-terminal tyrosine residue was incorporated to facilitate radiolabelling for pharmacokinetic research studies, and has since become a standard part of the compounds structure as used in laboratory research
