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Regarding the type of AEs, 18 patients (13.1%) reported insomnia, 15 patients (10.9%) reported widespread shivering, 10 patients (7.3%) reported headache, and 5 patients (3.6%) reported nausea (Table 3)
Although it probably represents a benign histological curiosity, its significance lies in the occasional case in which presence of this change may be mistaken for malignant melanoma
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Contudo, o acompanhamento clnico deve ser realizado, especialmente se houver fatores de risco para cncer oral, como histrico familiar, tabagismo e exposio solar excessiva
