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Normalization of this crucial ratio enhances the activity of phosphoethanolamine methyltransferase, restores normal synthesis of phosphatidylcholine to reduce fat deposition (112), reactivates the repair response mediated by protein L-isoaspartate methyltransferase (111), and attenuates liver damage caused by reduced methylation of the protein phosphatase 2a (PP2A) catalytic subunit (115)

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If you suspect you might have a B12 deficiency, the best place to start is with a medical evaluation