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In contrast to FDGbased imaging, [ 18 F] fluorinated glutamine ( 18 FFGln) displays low background uptake in brain tissues, and has been successfully used for tumor detection in mouse models of glioma and in glioma patients (Lieberman et al , 2011

Indeed, the apical localisation of SOP enzymes in human colonic crypts places this pathway optimally at the hostmicrobiome interface

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