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Screening techniques for DPN, such as the 10-g monofilament and assessment of touch, vibration sense, and ankle reflexes, have limitations, primarily detecting advanced neuropathy and missing early stages, especially those associated with small fiber abnormalities and neuropathic pain [14, 17,18,19,20,21,22]

Additionally, macrophages, natural killer cells, and mast cells also produce LL-37

[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Braeckman B.P., Smolders A., Back P., De Henau S

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