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In turn, increased fat oxidation could lead to weight loss over a longer period of time

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By pre-incubating the lactate-treated cells with the P300 inhibitor A485 or GPR81 siRNA, our findings revealed that, except for the downregulation of SOX2 expression in T47D cells, neither P300 (Fig

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Gen Hosp Psychiatry 24 , 106109 (2002)

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The decreased activity of this complex at ZT4 could be the result of a deficient SIRT3-dependent deacetylation of the complex II catalytic subunit SDHA in cKOt mice caused by the decrease in NAD + concentration (45, 46)

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