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Indeed, measurements of noradrenaline (NA)-induced aerobic glycolysis by FRET nanosensors in individual astrocytes demonstrated an increased glucose utilisation, manifested as reduced NA-elevated free cytosolic glucose concentration, whereas the production of lactate by NA was unaltered
Upregulation of TALDO, an enzyme linked to the pentose phosphate pathway enzyme which generates NADPH a key co-factor involved in anti-oxidant pathways, could suggest heightened levels oxidative stress (Ciregia et al., 2019
Telikepalli, S
doi: 10.1016/j.freeradbiomed.2018.03.042 74 FearonUCanavanMBinieckaMVealeDJ
