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J Cell Mol Med 25(21):1007310087 Huber R, Marcourt L, Hritier M, Luscher A, Guebey L, Schnee S, Michellod E, Guerrier S, Wolfender JL, Scapozza L, Khler T, Gindro K, Queiroz EF (2023) Generation of potent antibacterial compounds through enzymatic and chemical modifications of the trans--viniferin scaffold

To demonstrate this, we treated the stimulated PMN cells with compound 102 (125 M) and Zileuton (1 M)

Lipid peroxidation reactions are catalyzed by two types of enzymes: one is lipoxygenase (LOX), which catalyzes the production of toxic products such as MDA and 4-HNE from phosphatidylethanolamine (PE)-PUFAs

In other studies, medical ozone has typically been administered at a dose of 520 mL, ranging from 3 to 5 times per day, demonstrating both safety and efficacy in various clinical settings
