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Description
It is one of the five causes covered in the next section

doi: 10.1016/j.ymthe.2023.09.004

194,195 The activated PI3K catalyzes the conversion of membrane phospholipid Phosphatidylinositol-4,5-bisphosphate (PIP2) into Phosphatidylinositol-3,4,5-trisphosphate (PIP3)

Beyond its ROCK inhibition, it has inhibitory action against norepinephrine transporter (NET), making it a ROCK/NET inhibitor
