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J Inherited Metab Dis 20 : 270285
6 AltmanJ
This phosphorylation modification acts as a brake signal, inhibiting the activity of eIF2 and significantly reducing global protein synthesis to maintain cell survival, (Harding et al., 2003)
This increase in partial pressure of gases allows oxygen to be pushed into the bloodstream more efficiently, allowing more red blood cells to pick up more oxygen and, in turn, increases oxygen supply to damaged tissues
