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were the first to reveal the negative association between the expression of miR-199a-3p and mTOR, c-Met and Stat3 (Duan et al., 2011)

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The phosphorylated Gab1 creates additional binding sites for most downstream signaling molecules, which activate the different signaling pathways, including JAK/STAT3, phosphoinositide 3-kinase (PI3K)/Akt/NF-B, Ras/Raf, and mitogen-activated protein kinase (MAPK) cascades