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Arch Gen Psychiatry 57 : 11391147

While the physiological relevance of this system requires further in vivo investigation, its components, GluK3, Neto proteins, and synaptically released zinc are all known to be present at key central synapses, such as the hippocampal mossy fiber-CA3 synapse, a locus for synaptic plasticity and memory formation 15,33 , 34 , 18 , 35 ,
