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Chelation therapy, including nonabsorbed agents, should be initiated at a low dose and then gradually titrated to recommended doses according to the individual's response, to avoid the patient's health deteriorating with metal redistribution, other physiological perturbations, or drug intolerance

doi: 10.1007/978-3-319-63245-2_8 21 EndaleHTTesfayeWMengstieTA

Data availability Enquiries about data availability should be directed to the authors