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Pozzi V, Mazzotta M, Muzio LL, Sartini D, Santarelli A, Renzi E, Rocchetti R, Tomasetti M, Ciavarella D, Emanuelli M (2011) Inhibiting proliferation in KB cancer cells by RNA interference-mediated knockdown of nicotinamide N-methyltransferase expression

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this observation suggests that inactivation of the GPx3 gene by hypermethylation of the promoter may contribute to breast cancer progression