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Description
Analysis of the lipid deposition patterns in immune cells revealed that, compared with myeloid cells, CD4+ T cells were more enriched in PUFA-PLs (substrates of LPO), making these cells highly sensitive to ferroptosis (56)
22:2046 [DOI] [PubMed] [Google Scholar] 31.Jones RG, Pearce EJ
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Implications for clinical therapy Although, overall, both insulin sensitivity and beta-cell secretion are expected to improve with lowered glucose, HOMA-IR measurements over 8 weeks cannot be used to evaluate the effectiveness of treatment for an individual
