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10.1016/j.cmet.2014.07.006 80 KoethR

Cox cytochrome c oxidase subunit Drp-1 dynamin-related protein-1 Fis-1 fission protein LC3A/B light chain 3 microtubule associated protein A/B MnSOD manganese superoxide dismutase Opa-1 optic atrophy 1 OXPHOS oxidative phosphorylation P postnatal Pink-1 phosphatase and tensin homolog induced putative kinase ROS reactive oxygen species SE cigarette smoke exposed SELC SE breeders supplied with L-Carnitine Tom-20 translocase of outer membrane-20

Mechanistically, these flavonoids increased dichlorofluorescein (DCF) oxidation, suggesting their ability to elevate intracellular ROS levels and activate p38 Mitogen-activated protein kinases (MAPKs)

Should not be used as a substitute for a balanced diet