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Research by Kwon and Park involving 32 white rabbits divided into four groups explored the extent of cartilage degeneration following exposure to a placebo, AOD 9604 alone, hyaluronic acid alone, or a combination of AOD 9604 and hyaluronic acid over a period of 4 to 7 weeks

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Development and Selectivity The development of AOD9604 was based on the observation that the C-terminal region of growth hormone possesses independent metabolic regulatory functions distinct from the growth-promoting effects mediated by the N-terminal receptor-binding domain