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Multiple Sclerosis and Fatigue Management Patients with multiple sclerosis often experience significant fatigue that affects daily function

Protocol for a phase II, monocentre, double-blind, placebo-controlled, cross-over trial to assess efficacy of pyridostigmine in patients with spinal muscular atrophy types 24 (SPACE trial)

[sources 8] Psychological At normal therapeutic doses, the most common psychological side effects of amphetamine include increased alertness, apprehension, concentration, initiative, self-confidence and sociability, mood swings (elated mood followed by mildly depressed mood), insomnia or wakefulness, and decreased sense of fatigue
In a 12 months RCT, obese patients receiving 2000 IU vitamin D daily and lifestyle-based weight loss programme did not have significant reduction in body weight, body composition, BMI, insulin and C-reactive protein (CRP) levels when compared with the placebo group who received lifestyle-based weight loss programme only (Reference Mason, Xiao and Imayama50)
