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3.5.4 Macrophage ferroptosis and SLE Renal M2-like macrophages in LN patients selectively express CD163 (haptoglobinhemoglobin complex scavenger) and SLC40A1, tied to iron homeostasis (219, 220): 1) SLE-associated autoimmune hemolysis and glomerular injury-induced erythrocyte lysis generate excess haptoglobinhemoglobin complexes

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To further support these findings, we also detected activated caspases 3/7, an apoptotic marker, using a fluorescent dye (CellEvent