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Abstract Neurological disorders are defined by a deterioration or disruption of the nervous systems structure and function

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Brain abnormalities resulting from chronic use of heroin, oxycodone, and other morphine-derived drugs are underlying causes of opioid dependence (the need to keep taking drugs to avoid a withdrawal syndrome) and addiction (intense drug craving and compulsive use)

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Preman, P

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Its derivative, 5-methyl-THF, is the predominant active form of folate in blood and supports the conversion of methionine to SAM for methylation processes

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