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Compared with traditional L-T4 preparations (tablets), these new types of L-T4 preparations at the same dose perform better in suppressing the serum TSH values and obtaining normal thyroid hormone levels, especially in pregnant women [101], unselected patients without evident malabsorption [102, 103] and even euthyroid patients [104]

Therapeutic modulation of the microbiome shows promise: antibiotics targeting dysbiotic bacteria and fecal microbiota transfer (FMT) reduce lesion growth in preclinical models, while probiotics restoring Lactobacillus dominance improve NK cell activity and reproductive outcomes

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