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Description
GLPs drive fat loss but can reduce lean muscle mass
However, with the passage of time, the motor function deteriorated in most of the groups (Grade 1.2 to 2.3 at 16 weeks post SNR) with the exception of Groups 7 and 8 (Grade 3.0) that received G-CSF and Dihexa, respectively, to the gastrocnemius muscle (Table 2)
Metformin might help aid weight loss, as it helps stabilise blood sugar levels so there are less glucose fluctuations which is what increases hunger or even leads to overeating
At 12mg weekly, trials show 24.2% weight loss at 48 weeks and up to 28.7% at 68 weeks in Phase 3
