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Description
Living skin has blood circulation that clears delivered molecules at a rate the Franz cell does not capture, and a longer functional half-life of the peptide in tissue is implied but not directly measured

115 MozaffarianD.BenjaminE

doi: 10.3389/fpls.2015.00799 25 RamakrishnaWKumariARahmanNMandaveP

Prostaglandins are synthetized in the endothelium and show vasodilator and anti-inflammatory effects
