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This disruption of immune tolerance contributes to the development and progression of autoimmune diseases [142]
For instance, subnormal levels of aminotransferases can be observed in vitamin B 6 deficiency and chronic kidney disease
However, the association of auto-antibodies toward the P/Q-type VGCC with CAs was also described in patients with paraneoplastic cerebellar degeneration (PCD) with or without LEMS [38], especially in LEMS-positive patients [39] (Table 2)
