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[11] found that NNMT expression levels are elevated in WAT and the liver of the T2D mice and that NNMT knockdown improves the glucose tolerance and insulin sensitivity in the T2D mice
PLoS One 2015;10:e0129915 10.1371/journal.pone.0129915 [DOI] [PMC free article] [PubMed] [Google Scholar] 17

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These cholesterol reductions brought levels comparable to those seen in lean, healthy control mice, suggesting comprehensive metabolic normalization
